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Article

A journey through the lectin pathway of complement—<scp>MBL</scp> and beyond

26 Oct 2016

Abstract excerpt

Mannose-binding lectin (MBL), collectin-10, collectin-11, and the ficolins (ficolin-1, ficolin-2, and ficolin-3) are soluble pattern recognition molecules in the lectin complement pathway. These proteins act as mediators of host defense and participate in maintenance of tissue homeostasis. They bind to conserved pathogen-specific structures and altered self-antigens and form complexes with the pentraxins to...

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PMID: 27782323
DOI: 10.1111/imr.12468

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