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Article

Components of the lectin pathway of complement activation in paediatric patients of intensive care units.

Immunobiology - 1 May 2016

Świerzko Anna S, Szala-Poździej Agnieszka, Kilpatrick David C, Sobociński Michał, Chojnacka Karolina, Sokołowska Anna, Michalski Mateusz, Mazerant Karolina, Jensenius Jens C, Matsushita Misao, Krajewski Wojciech R, Szczapa Jerzy, Bąk-Romaniszyn Leokadia, Zeman Krzysztof, Cedzyński Maciej

Abstract excerpt

Infections are a major cause of childhood mortality. We investigated components of the lectin pathway of complement activation in the context of sepsis at both genetic and protein levels in neonates, infants and older children. Major components of the lectin pathway and two genes for Toll-like receptors were studied in 87 neonates with confirmed sepsis and compared with 40 babies with infections who did not...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26850322
DOI: 10.1016/j.imbio.2016.01.003

Genes

FCN1
FCN2
FCN3
MASP1
MASP2
TLR2
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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