Article
Mannose-binding lectin genotypes and pre-eclampsia: a case-control study.
Human immunology - 1 Nov 2007
van de Geijn Fleur E, Dolhain Radboud J E M, van Rijs Wouter, Hazes Johanna M W, de Groot Christianne J M
Abstract excerpt
Both immunological and placental factors are involved in the pathogenesis of pre-eclampsia. The complement factor mannose-binding lectin (MBL) is associated with adverse pregnancy outcomes and has been suggested to play a role in abnormal placentation. We investigated whether MBL genotypes are associated with the systemic maternal syndrome pre-eclampsia. MBL2 gene polymorphisms were determined in a case-control...
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