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Article

Novel MASP2 variants detected among North African and Sub-Saharan individuals.

Tissue antigens - 1 Aug 2005

Lozano F, Suárez B, Muñoz A, Jensenius J C, Mensa J, Vives J, Horcajada J-P

Abstract excerpt

The lectin pathway of the complement system is activated when mannan-binding lectin (MBL) in complex with MBL-associated serine protease 2 (MASP-2) binds to carbohydrate structures on microorganisms. Structural gene mutations and promoter polymorphisms in the MBL2 gene responsible for low-MBL serum levels are present in all human populations and associate with increased risk of infection. Recently, investigations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Complement C4

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Source

Identifiers

PMID: 16029433
DOI: 10.1111/j.1399-0039.2005.00436.x

Genes

MASP2
MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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