Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mannose-binding lectin and its genetic variants.

Genes and immunity - 1 Mar 2006

Garred P, Larsen F, Seyfarth J, Fujita R, Madsen H O

Abstract excerpt

Mannose-binding lectin (MBL) is a collagen-like serum protein that mediates activation of the complement system and is of importance for host defence. Common variant alleles situated both in the promoter and structural region of the human MBL gene (MBL2) influence the stability and the serum concentration of the protein. Epidemiological studies have suggested that genetically determined variation in MBL serum...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Complement system in diseases
Share to MBL2 gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Mannose-Binding Lectin

Share to Models, Genetic

Share to Monoclonal and Polyclonal Antibodies Research

Share to Platelet Disorders and Treatments

Source

Identifiers

PMID: 16395391
DOI: 10.1038/sj.gene.6364283

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mannose-binding lectin and its genetic variants.PMID 16395391Read ↗

Mannose-binding lectin genetics: from A to Z.Semantic proximity Read ↗

Mannose-binding lectin: structure, function, genetics and disease associations.Semantic proximity Read ↗

Characterization of mannose-binding lectin (MBL) variants by allele-specific sequencing of MBL2 and determination of serum MBL protein levels.Semantic proximity Read ↗

Biochemistry and genetics of mannan-binding lectin (MBL)Semantic proximity Read ↗

MBL2, FCN1, FCN2 and FCN3-The genes behind the initiation of the lectin pathway of complement.Semantic proximity Read ↗

Mannan-binding lectin deficiency - Good news, bad news, doesn't matter?Semantic proximity Read ↗

Mannose-binding lectin and MBL-associated serine protease-2 gene polymorphisms in a Brazilian population from Rio de Janeiro.Semantic proximity Read ↗

Genetic and structural analysis of MBL2 and MASP2 polymorphisms in south-eastern African children.Semantic proximity Read ↗

Mannose-binding lectin deficiency--revisited.Semantic proximity Read ↗

Evolutionary insights into the high worldwide prevalence of MBL2 deficiency alleles.Semantic proximity Read ↗

Mannan-binding lectin: clinical significance and applications.Semantic proximity Read ↗

Mannose binding lectin and susceptibility to rheumatoid arthritis in Brazilian patients and their relatives.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.