Article
MBL2 variations and malaria susceptibility in Indian populations.
Infection and immunity - 1 Jan 2014
Jha Aditya Nath, Sundaravadivel Pandarisamy, Singh Vipin Kumar, Pati Sudhanshu S, Patra Pradeep K, Kremsner Peter G, Velavan Thirumalaisamy P, Singh Lalji, Thangaraj Kumarasamy
Abstract excerpt
Human mannose-binding lectin (MBL) encoded by the MBL2 gene is a pattern recognition protein and has been associated with many infectious diseases, including malaria. We sought to investigate the contribution of functional MBL2 gene variations to Plasmodium falciparum malaria in well-defined cases and in matched controls. We resequenced the 8.7 kb of the entire MBL2 gene in 434 individuals clinically classified...
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