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Article

Genetic polymorphisms of mannose-binding lectin do not influence placental malaria but are associated with preterm deliveries.

Infection and immunity - 1 Apr 2009

Thévenon Audrey D, Leke Rose G F, Suguitan Amorsolo L, Zhou James A, Taylor Diane Wallace

Abstract excerpt

During pregnancy, Plasmodium falciparum-infected erythrocytes (IE) sequester in the placenta where they induce pathology and increase the risk of low-birth-weight (LBW) babies. The innate immune mediator, mannose-binding lectin (MBL), enhances phagocytosis of pathogens. Since MBL is reported to bind to IE, we hypothesized that it might aid in clearance of IE from the placenta, thereby reducing the risk of LBW...

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Source

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Identifiers

PMID: 19139195
DOI: 10.1128/IAI.01069-08
PMCID: PMC2663154

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic polymorphisms of mannose-binding lectin do not influence placental malaria but are associated with preterm deliveries.PMID 19139195Read ↗

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