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Article

Expression and function of mutant Ia antigen in transgenic mice.

Transplantation - 1 Oct 1990

Wei B Y, Martin J, Little R, Anderson G, Savarirayan S, Buerstedde J M, McKean D, David C

Abstract excerpt

Cell surface expression of Ia antigens requires the assembly of alpha and beta heterodimers. We have produced a double transgenic mouse with a wild form Ak alpha gene and a mutant Ak beta (Ak beta MB) gene with d-allele substitution at positions 63 and 65-67. Initial studies indicated that the Ak alpha and Ak beta MB transgenes are not expressed on the surface of lymphoid cells of the transgenic mice. However,...

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Identifiers

PMID: 2219292
DOI: 10.1097/00007890-199010000-00032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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