Expression of I-A alpha k and allelic restriction on A alpha/A beta pairing in transgenic mice.

doi:10.1111/j.1744-313x.1990.tb00867.x

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Article

Expression of I-A alpha k and allelic restriction on A alpha/A beta pairing in transgenic mice.

Journal of immunogenetics - 1 Jan 2000

Martin J, Wei B Y, Savarirayan S, David C S

Abstract excerpt

Cell surface expression of class 11 major histocompatibility complex encoded (1a) molecules depends on association of the component alpha and beta chain into a stable heterodimer. Studies on cell lines transfected with MHC class II genes have revealed important limitations on the assembly of hapl...

Topics

Alleles
Animals
Cell Line
Cell Membrane
Crosses, Genetic
Gene Expression
Genes, MHC Class II
Histocompatibility Antigens Class II
Mice
Mice, Transgenic

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