Article
Functional and phenotypic change of T cells in murine acquired immune deficiency.
Journal of immunology (Baltimore, Md. : 1950) - 1 May 1994
Kanagawa O, Gayama S, Vaupel B
Abstract excerpt
Infection of susceptible C57BL/6 mice with defective LP-BM5 murine leukemia virus causes disease termed murine acquired immune deficiency syndrome (MAIDS). The disease is characterized by lymphoadenopathy, hyperimmunoglobulinemia, and immune deficiency in both T and B cell functions. The development of disease requires the presence of mature T cells, especially CD4 T cells, and B cells. It has previously been...
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