Functional and phenotypic change of T cells in murine acquired immune deficiency.

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Article

Functional and phenotypic change of T cells in murine acquired immune deficiency.

Journal of immunology (Baltimore, Md. : 1950) - 1 May 1994

Kanagawa O, Gayama S, Vaupel B

Abstract excerpt

Infection of susceptible C57BL/6 mice with defective LP-BM5 murine leukemia virus causes disease termed murine acquired immune deficiency syndrome (MAIDS). The disease is characterized by lymphoadenopathy, hyperimmunoglobulinemia, and immune deficiency in both T and B cell functions. The development of disease requires the presence of mature T cells, especially CD4 T cells, and B cells. It has previously been...

Topics

Amino Acid Sequence
Animals
Base Sequence
DNA Primers
DNA, Viral
Gene Products, gag
Genes, gag
Hybridomas
Leukemia Virus, Murine
Mice
Mice, Inbred C57BL
Mice, Transgenic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Murine Acquired Immunodeficiency Syndrome

Phenotype

RNA, Viral

Receptors, Antigen, T-Cell, alpha-beta

Superantigens

Source

Open in PubMed

Identifiers

PMID: 8157980

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8157980-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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