Article
Find and replace: editing human genome in pluripotent stem cells.
Protein & cell - 1 Dec 2011
Pan Huize, Zhang Weiqi, Zhang Weizhou, Liu Guang-Hui
Abstract excerpt
Genetic manipulation of human pluripotent stem cells (hPSCs) provides a powerful tool for modeling diseases and developing future medicine. Recently a number of independent genome-editing techniques were developed, including plasmid, bacterial artificial chromosome, adeno-associated virus vector, zinc finger nuclease, transcription activator-like effecter nuclease, and helper-dependent adenoviral vector. Gene...
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