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Genome editing in induced pluripotent stem cells

4 Apr 2012

Abstract excerpt

The discovery of induced pluripotent stem (iPS) cells has broadened the promises of regenerative medicine through the generation of syngeneic replacement cells or tissues via the differentiation of patient-specific iPS cells. To apply iPS cell-mediated therapy to patients with genetic disorders, however, genome-editing technologies with high efficiency and specificity are needed. Recently, several targeted...

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PMID: 22487259
DOI: 10.1111/j.1365-2443.2012.01599.x

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