Article
Genome editing in pluripotent stem cells: research and therapeutic applications.
Biochemical and biophysical research communications - 6 May 2016
Deleidi Michela, Yu Cong
Abstract excerpt
Recent progress in human pluripotent stem cell (hPSC) and genome editing technologies has opened up new avenues for the investigation of human biology in health and disease as well as the development of therapeutic applications. Gene editing approaches with programmable nucleases have been successfully established in hPSCs and applied to study gene function, develop novel animal models and perform genetic and...
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