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Article

A Method for Genome Editing in Human Pluripotent Stem Cells.

Cold Spring Harbor protocols - 1 Apr 2016

Smith Cory, Ye Zhaohui, Cheng Linzhao

Abstract excerpt

Human pluripotent stem cells (PSCs) hold great potential for regenerative medicine and currently are being used as a research tool for basic discovery and disease modeling. To evaluate the role of a single genetic variant, a system of genome editing is needed to precisely mutate any desired DNA sequence in isolation and measure its effect on phenotype when compared to the isogenic parental PSC from which it was...

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Identifiers

PMID: 27037073
DOI: 10.1101/pdb.prot090217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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