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Combining Induced Pluripotent Stem Cells and Genome Editing Technologies for Clinical Applications

1 Mar 2018

Abstract excerpt

In this review, we introduce current developments in induced pluripotent stem cells (iPSCs), site-specific nuclease (SSN)-mediated genome editing tools, and the combined application of these two novel technologies in biomedical research and therapeutic trials. The sustainable pluripotent property of iPSCs in vitro not only provides unlimited cell sources for basic research but also benefits precision medicines...

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PMID: 29806481
DOI: 10.1177/0963689718754560

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