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Article

Effects of the val(158)met catechol-O-methyltransferase gene polymorphism on olfactory processing in schizophrenia.

Behavioral neuroscience - 1 Feb 2012

Kamath Vidyulata, Moberg Paul J, Gur Raquel E, Doty Richard L, Turetsky Bruce I

Abstract excerpt

The catechol-O-methyltransferase (COMT) val158met polymorphism has received attention in schizophrenia due to its role in prefrontal dopamine catabolism. Given the rich dopaminergic innervations of the olfactory bulb and the influence of dopamine on the transmission of olfactory signals, the authors examined the influence of COMT genotype status on the olfactory processing impairment observed in schizophrenia....

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 22148860
DOI: 10.1037/a0026466
PMCID: PMC3269516

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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