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Sex-dependent effect on the association of COMT Val158Met polymorphism with schizophrenia clinical symptoms and cognitive impairment

2021-08-26

Abstract excerpt

Catechol-O-methyltransferase ( COMT ) Val 158 Met (rs4680) polymorphism is thought to be involved in the pathogenesis of schizophrenia, which is related to the regulation of dopamine transmission in the prefrontal cortex. Recent studies have shown that the influence of COMT Val 158 Met variation is sexually dimorphic. This study aims to explore the possible effect of the interaction between COMT Val 158 Met polymo...

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Literature Corpus work
82e7bd96-98a6-5902-9583-bbc7e451b203
DOI
10.21203/rs.3.rs-817886/v1
Open publication

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Sex-dependent effect on the association of COMT Val158Met polymorphism with schizophrenia clinical symptoms and cognitive impairmentDOI 10.21203/rs.3.rs-817886/v1
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