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Article

Genetic association of catechol-O-methyltransferase val(158)met polymorphism in Saudi schizophrenia patients.

Genetics and molecular research : GMR - 17 Apr 2014

Al-Asmary S, Kadasah S, Arfin M, Tariq M, Al-Asmari A

Abstract excerpt

Schizophrenia is a complex neuropsychiatric disorder strongly associated with dopamine dysregulation. Catechol-O-methyl-transferase (COMT) is a candidate gene for schizophrenia that encodes an enzyme involved in the metabolic inactivation of dopamine. The COMT Val(158)Met polymorphism has been associated with schizophrenia and has significant inter- and intra-ethnic variations. We examined a possible association...

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Source

Identifiers

PMID: 24782165
DOI: 10.4238/2014.April.17.4

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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