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Article

Catechol O-methyltransferase variants and cognitive performance in schizophrenia and bipolar disorder versus controls.

Schizophrenia research - 1 Sept 2010

Wirgenes Katrine V, Djurovic Srdjan, Sundet Kjetil, Agartz Ingrid, Mattingsdal Morten, Athanasiu Lavinia, Melle Ingrid, Andreassen Ole A

Abstract excerpt

BACKGROUND: The gene encoding Catechol O-methyltransferase (COMT), a dopamine catabolic enzyme, is an important candidate gene in several psychiatric disorders. Several studies have shown an association between the functional Val(158)Met polymorphism and cognitive performance. However, the results have been inconsistent and there are few studies addressing other COMT single nucleotide polymorphisms (SNPs)....

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Source

Identifiers

PMID: 20605701
DOI: 10.1016/j.schres.2010.05.007

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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