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Article

Prefrontal neurons and the genetics of schizophrenia.

Biological psychiatry - 1 Dec 2001

Weinberger D R, Egan M F, Bertolino A, Callicott J H, Mattay V S, Lipska B K, Berman K F, Goldberg T E

Abstract excerpt

This article reviews prefrontal cortical biology as it relates to pathophysiology and genetic risk for schizophrenia. Studies of prefrontal neurocognition and functional neuroimaging of prefrontal information processing consistently reveal abnormalities in patients with schizophrenia. Abnormalities of prefrontal information processing also are found in unaffected individuals who are genetically at risk for...

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Identifiers

PMID: 11743939
DOI: 10.1016/s0006-3223(01)01252-5

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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