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Article

Catechol-O-methyltransferase Val158Met polymorphism in schizophrenia: associations with cognitive and motor impairment.

Neuropsychobiology - 1 Jan 2005

Galderisi Silvana, Maj Mario, Kirkpatrick Brian, Piccardi Paola, Mucci Armida, Invernizzi Giordano, Rossi Alessandro, Pini Stefano, Vita Antonio, Cassano Paolo, Stratta Paolo, Severino Giovanni, Del Zompo Maria

Abstract excerpt

Cognitive and motor deficits have been proposed as markers of abnormal neurodevelopment in schizophrenia and have been associated with genetic liability. In a multicenter study involving 106 subjects, 56 with deficit schizophrenia and 50 with nondeficit schizophrenia, we tested the hypothesis tha...

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Source

Identifiers

PMID: 16037677
DOI: 10.1159/000087096

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16037677-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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