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Article

Insulin receptor-mediated signaling via phospholipase C-γ regulates growth and differentiation in Drosophila.

PloS one - 1 Jan 2011

Murillo-Maldonado Juan M, Zeineddine Fouad Bou, Stock Rachel, Thackeray Justin, Riesgo-Escovar Juan R

Abstract excerpt

Coordination between growth and patterning/differentiation is critical if appropriate final organ structure and size is to be achieved. Understanding how these two processes are regulated is therefore a fundamental and as yet incompletely answered question. Here we show through genetic analysis that the phospholipase C-γ (PLC-γ) encoded by small wing (sl) acts as such a link between growth and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22132213
DOI: 10.1371/journal.pone.0028067
PMCID: PMC3221684

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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