Article
small wing encodes a phospholipase C-(gamma) that acts as a negative regulator of R7 development in Drosophila.
Development (Cambridge, England) - 1 Dec 1998
Thackeray J R, Gaines P C, Ebert P, Carlson J R
Abstract excerpt
Phospholipase C-(gamma) (PLC-(gamma)) is activated in many cell types following growth factor stimulation. Our understanding of the role of PLC-(gamma) in cell growth and differentiation has been severely limited by the dearth of mutations in any organism. In this study, we show that the Drosophila gene small wing (sl), identified by Bridges in 1915, encodes a PLC-(gamma). Mutations of sl result in extra R7...
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