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Article

Transient but not stable ZEB1 knockdown dramatically inhibits growth of malignant pleural mesothelioma cells.

Annals of surgical oncology - 1 Jul 2012

Horio Mihoko, Sato Mitsuo, Takeyama Yoshihiro, Elshazley Momen, Yamashita Ryo, Hase Tetsunari, Yoshida Kenya, Usami Noriyasu, Yokoi Kohei, Sekido Yoshitaka, Kondo Masashi, Toyokuni Shinya, Gazdar Adi F, Minna John D, Hasegawa Yoshinori

Abstract excerpt

BACKGROUND: The role of ZEB1, a master epithelial-to-mesenchymal transition gene, in malignant pleural mesothelioma (MPM) is unclear. METHODS: The expression of ZEB1, E-cadherin, vimentin, and epithelial cell adhesion molecule (EpCAM) in 18 MPM cell lines and a normal pleural mesothelial cell line MeT-5A was determined by quantitative real-time polymerase chain reaction and Western blot testing. RNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22086445
DOI: 10.1245/s10434-011-2142-0
PMCID: PMC3413790

Genes

ZEB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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