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Article

Epithelial-mesenchymal transition in malignant mesothelioma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jan 2012

Fassina Ambrogio, Cappellesso Rocco, Guzzardo Vincenza, Dalla Via Lisa, Piccolo Stefano, Ventura Laura, Fassan Matteo

Abstract excerpt

Epithelial-mesenchymal transition is a physiopathological process by which epithelial cells acquire mesenchymal shape and properties. Malignant mesothelioma is histologically characterized by the concomitant presence of epithelioid and sarcomatoid features, the latter being associated to worse prognosis, thus suggesting a role of epithelial-mesenchymal transition in this dual phenotype. We studied 109 malignant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21983934
DOI: 10.1038/modpathol.2011.144

Genes

ZEB1
ZEB2
MMP2
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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