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Article

CDKN2A Determines Mesothelioma Cell Fate to EZH2 Inhibition

1 Jul 2021

Abstract excerpt

Malignant pleural mesothelioma is an aggressive cancer, heterogeneous in its presentation and behaviour. Despite an increasing knowledge about molecular markers and their diagnostic and prognostic value, they are not used as much as they might be for treatment allocation. It has been recently reported that mesothelioma cells that lack BAP1 (BRCA1 Associated Protein) are sensitive to inhibition of the EZH2...

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PMID: 34277422
DOI: 10.3389/fonc.2021.678447

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