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Article

Copy number and loss of heterozygosity detected by SNP array of formalin-fixed tissues using whole-genome amplification.

PloS one - 1 Jan 2011

Stokes Angela, Drozdov Ignat, Guerra Eliete, Ouzounis Christos A, Warnakulasuriya Saman, Gleeson Michael J, McGurk Mark, Tavassoli Mahvash, Odell Edward W

Abstract excerpt

The requirement for large amounts of good quality DNA for whole-genome applications prohibits their use for small, laser capture micro-dissected (LCM), and/or rare clinical samples, which are also often formalin-fixed and paraffin-embedded (FFPE). Whole-genome amplification of DNA from these samples could, potentially, overcome these limitations. However, little is known about the artefacts introduced by...

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PMID: 21966361
DOI: 10.1371/journal.pone.0024503
PMCID: PMC3180289

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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