Article
Single nucleotide polymorphism microarray analysis of genetic alterations in cancer.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011
Mullighan Charles G
Abstract excerpt
The identification of structural genetic alterations, including DNA amplifications, deletions, and loss of heterozygosity (LOH), using single nucleotide polymorphism (SNP) microarrays has provided important insights into the pathogenesis of a number of hematologic malignancies. Currently available SNP arrays comprise over a million SNP and copy number oligonucleotide probes that interrogate the genome at...
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