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Article

Whole genome amplification of DNA from laser capture-microdissected tissue for high-throughput single nucleotide polymorphism and short tandem repeat genotyping.

The American journal of pathology - 1 Jan 2004

Rook Martha S, Delach Scott M, Deyneko Galina, Worlock Andrew, Wolfe Jia Liu

Abstract excerpt

Genome-wide screening of genetic alterations between normal and cancer cells, as well as among subgroups of tumors, is important for establishing molecular mechanism and classification of cancer. Gene silencing through loss of heterozygosity is widely observed in cancer cells and detectable by analyzing allelic loss of single nucleotide polymorphism and/or short tandem repeat markers. To use minute quantities of...

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Identifiers

PMID: 14695315
DOI: 10.1016/S0002-9440(10)63092-1
PMCID: PMC1602222

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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