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Article

Genomewide scan for loss of heterozygosity and chromosomal amplification in breast carcinoma using single-nucleotide polymorphism arrays.

Cancer genetics and cytogenetics - 15 Apr 2008

Argos Maria, Kibriya Muhammad G, Jasmine Farzana, Olopade Olufunmilayo I, Su Tao, Hibshoosh Hanina, Ahsan Habibul

Abstract excerpt

In an effort to identify novel genes implicated in breast carcinogenesis, a genomewide scan for loss of heterozygosity (LOH) and copy number changes in paired-DNA samples extracted from normal and tumor tissue of frozen sections from women undergoing surgery for invasive breast cancer was conducted. The Affymetrix 10K SNP array was used to examine genomewide LOH of chromosomal regions. The number of LOH events,...

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Identifiers

PMID: 18406867
DOI: 10.1016/j.cancergencyto.2008.01.001
PMCID: PMC3972020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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