Article
The mechanism of group I self-splicing: an internal guide sequence can be provided in trans.
The EMBO journal - 1 Jun 1990
Winter A J, Groot Koerkamp M J, Tabak H F
Abstract excerpt
We have reconstituted a group I self-splicing reaction between two RNA molecules with different functional RNA parts: a substrate molecule containing the 5' splice site and a functional internal guide sequence (IGS), and a ribozyme molecule with core structure elements and splice sites but a muta...
Topics
- Animals
- Base Sequence
- Catalysis
- Exons
- Introns
- Models, Molecular
- Molecular Sequence Data
- Mutation
- RNA Precursors
- RNA Splicing
- RNA, Catalytic
- RNA, Ribosomal
- Tetrahymena