Article
Reverse self-splicing of group II intron RNAs in vitro.
Nature - 25 Jan 1990
Augustin S, Müller M W, Schweyen R J
Abstract excerpt
Group II introns, which are classed together on the basis of a conserved secondary structure, are found in organellar genes of lower eukaryotes and plants. Like introns in nuclear pre-messenger RNA, they are excised by a two-step splicing reaction to generate branched circular RNAs, the so-called lariats. A remarkable feature of group II introns is their self-splicing activity in vitro. In the absence of a...
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