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Article

Self-splicing of a group I intron reveals partitioning of native and misfolded RNA populations in yeast.

RNA (New York, N.Y.) - 1 Dec 2006

Jackson Scott A, Koduvayur Sujatha, Woodson Sarah A

Abstract excerpt

Stable RNAs must form specific three-dimensional structures, yet many RNAs become kinetically trapped in misfolded conformations. To understand the factors that control the accuracy of RNA folding in the cell, the self-splicing activity of the Tetrahymena group I intron was compared in different genetic contexts in budding yeast. The extent of splicing was 98% when the intron was placed in its natural rDNA...

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Source

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Identifiers

PMID: 17135489
DOI: 10.1261/rna.184206
PMCID: PMC1664722

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Self-splicing of a group I intron reveals partitioning of native and misfolded RNA populations in yeast.PMID 17135489Read ↗

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