Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A boundary element between Tsix and Xist binds the chromatin insulator Ctcf and contributes to initiation of X-chromosome inactivation.

Genetics - 1 Oct 2011

Spencer Rebecca J, del Rosario Brian C, Pinter Stefan F, Lessing Derek, Sadreyev Ruslan I, Lee Jeannie T

Abstract excerpt

In mammals, X-chromosome inactivation (XCI) equalizes X-linked gene expression between XY males and XX females and is controlled by a specialized region known as the X-inactivation center (Xic). The Xic harbors two chromatin interaction domains, one centered around the noncoding Xist gene and the other around the antisense Tsix counterpart. Previous work demonstrated the existence of a chromatin transitional zone...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CCCTC-Binding Factor
Share to Chromatin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromatin Immunoprecipitation

Share to Electrophoretic Mobility Shift Assay

Share to Mice, 129 Strain

Share to RNA, Long Noncoding

Share to RNA, Untranslated

Share to X Chromosome Inactivation

Source

Open in PubMed Open full text

Identifiers

PMID: 21840866
DOI: 10.1534/genetics.111.132662
PMCID: PMC3189804

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A boundary element between Tsix and Xist binds the chromatin insulator Ctcf and contributes to initiation of X-chromosome inactivation.PMID 21840866Read ↗

Tsix RNA and the germline factor, PRDM14, link X reactivation and stem cell reprogramming.Semantic proximity Read ↗

High-resolution analysis of epigenetic changes associated with X inactivation.Semantic proximity Read ↗

Sensing X chromosome pairs before X inactivation via a novel X-pairing region of the Xic.Semantic proximity Read ↗

KDM6A facilitates Xist upregulation at the onset of X inactivationSemantic proximity Read ↗

Advances in understanding chromosome silencing by the long non-coding RNA Xist.Semantic proximity Read ↗

Tsix transcription across the Xist gene alters chromatin conformation without affecting Xist transcription: implications for X-chromosome inactivation.Semantic proximity Read ↗

A Novel <i>XACT</i> lncRNA Transcript with Functions Transcending X-Chromosome InactivationSemantic proximity Read ↗

Xist and Tsix Transcription Dynamics Is Regulated by the X-to-Autosome Ratio and Semistable Transcriptional States.Semantic proximity Read ↗

Unleashing XIST from X-chromosome inactivationSemantic proximity Read ↗

Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region.Semantic proximity Read ↗

A 94 kb genomic sequence 3' to the murine Xist gene reveals an AT rich region containing a new testis specific gene TsxSemantic proximity Read ↗

NF-κB Signaling is Required for X-Chromosome Inactivation Maintenance Following T cell ActivationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.