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Article

Performance of ultra-deep pyrosequencing in analysis of HIV-1 pol gene variation.

PloS one - 1 Jan 2011

Mild Mattias, Hedskog Charlotte, Jernberg Johanna, Albert Jan

Abstract excerpt

INTRODUCTION: Ultra-deep pyrosequencing (UDPS) has been used to detect minority variants within HIV-1 populations. Some aspects of the quality and reproducibility of UDPS have been previously evaluated, but comprehensive studies are still needed. PRINCIPAL FINDING: In this study the UDPS technology (FLX platform) was evaluated by analyzing a 120 base pair fragment of the HIV-1 pol gene from plasma samples from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21799940
DOI: 10.1371/journal.pone.0022741
PMCID: PMC3143174

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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