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Article

Variants in GLIS3 and CRY2 are associated with type 2 diabetes and impaired fasting glucose in Chinese Hans.

PloS one - 1 Jan 2011

Liu Chen, Li Huaixing, Qi Lu, Loos Ruth J F, Qi Qibin, Lu Ling, Gan Wei, Lin Xu

Abstract excerpt

BACKGROUND: Recent genome-wide association studies have identified a number of common variants associated with fasting glucose homeostasis and type 2 diabetes in populations of European origin. This is a replication study to examine whether such associations are also observed in Chinese Hans. METHODS: We genotyped nine variants in or near MADD, ADRA2A, CRY2, GLIS3, PROX1, FADS1, C2CD4B, IGF1 and IRS1 in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 21747906
DOI: 10.1371/journal.pone.0021464
PMCID: PMC3126830

Genes

CRY2
GLIS3
FADS1
IGF1
IRS1
MADD
PROX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Variants in GLIS3 and CRY2 are associated with type 2 diabetes and impaired fasting glucose in Chinese Hans.PMID 21747906Read ↗

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Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people.Semantic proximity Read ↗

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Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.Semantic proximity Read ↗

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Variations with modest effects have an important role in the genetic background of type 2 diabetes and diabetes-related traits.Semantic proximity Read ↗

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