Article
Replication study for the association of 9 East Asian GWAS-derived loci with susceptibility to type 2 diabetes in a Japanese population.
PloS one - 1 Jan 2013
Sakai Kensuke, Imamura Minako, Tanaka Yasushi, Iwata Minoru, Hirose Hiroshi, Kaku Kohei, Maegawa Hiroshi, Watada Hirotaka, Tobe Kazuyuki, Kashiwagi Atsunori, Kawamori Ryuzo, Maeda Shiro
Abstract excerpt
AIMS: East Asian genome-wide association studies (GWAS) for type 2 diabetes identified 8 loci with genome-wide significance, and 2 loci with a borderline association. However, the associations of these loci except MAEA locus with type 2 diabetes have not been evaluated in independent East Asian cohorts. We performed a replication study to investigate the association of these susceptibility loci with type 2...
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