Article
A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.
Diabetes - 1 Jan 2013
Li Huaixing, Gan Wei, Lu Ling, Dong Xiao, Han Xueyao, Hu Cheng, Yang Zhen, Sun Liang, Bao Wei, Li Pengtao, He Meian, Sun Liangdan, Wang Yiqin, Zhu Jingwen, Ning Qianqian, Tang Yong, Zhang Rong, Wen Jie, Wang Di, Zhu Xilin, Guo Kunquan, Zuo Xianbo, Guo Xiaohui, Yang Handong, Zhou Xianghai, Zhang Xuejun, Qi Lu, Loos Ruth J F, Hu Frank B, Wu Tangchun, Liu Ying, Liu Liegang, Yang Ze, Hu Renming, Jia Weiping, Ji Linong, Li Yixue, Lin Xu
Abstract excerpt
Substantial progress has been made in identification of type 2 diabetes (T2D) risk loci in the past few years, but our understanding of the genetic basis of T2D in ethnically diverse populations remains limited. We performed a genome-wide association study and a replication study in Chinese Hans comprising 8,569 T2D case subjects and 8,923 control subjects in total, from which 10 single nucleotide polymorphisms...
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