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Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.

Diabetes - 1 Oct 2008

Wu Ying, Li Huaixing, Loos Ruth J F, Yu Zhijie, Ye Xingwang, Chen Lihua, Pan An, Hu Frank B, Lin Xu

Abstract excerpt

OBJECTIVE: Genome-wide association studies have identified common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, HHEX/IDE, EXT2, and LOC387761 loci that significantly increase the risk of type 2 diabetes. We aimed to replicate these observations in a population-based cohort of Chinese Hans and examine the associations of these variants with type 2 diabetes and diabetes-related phenotypes. RESEARCH DESIGN AND...

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Identifiers

PMID: 18633108
DOI: 10.2337/db08-0047
PMCID: PMC2551696

Genes

CDKAL1
HHEX
IDE
EXT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.PMID 18633108Read ↗

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