Article
Gli-similar 3 (GLIS3) rs7020763 (C>G) polymorphism in patients with type 2 diabetes mellitus.
The Egyptian journal of immunology - 1 Oct 2022
Mohamed Lubna E, Elhadidi Eman S, Saad Wessam E, Maher Maram M, Yousry Walaa A
Abstract excerpt
Type 2 diabetes mellitus (T2DM) is a heterogeneous group of metabolic disorders characterized by the incapability of pancreatic beta cells to increase insulin secretion to compensate for insulin resistance in the peripheral tissues. T2DM is a multi-factorial disease including several environmental factors with the presence of genetic predisposition. The transcription factor GLI-Similar 3 (GLIS3) has an important...
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