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Article

Loss of MTBP expression is associated with reduced survival in a biomarker-defined subset of patients with squamous cell carcinoma of the head and neck.

Cancer - 1 Jul 2011

Vlatković Nikolina, El-Fert Ashraf, Devling Timothy, Ray-Sinha Arpita, Gore David M, Rubbi Carlos P, Dodson Andy, Jones Andrew S, Helliwell Tim R, Jones Terence M, Boyd Mark T

Abstract excerpt

BACKGROUND: Recent genetic studies have implicated p53 mutation as a significant risk factor for therapeutic failure in squamous cell carcinoma of the head and neck (SCCHN). However, in a recent meta-analysis in the literature of p53 from major anatomical subsites (larynx, oral cavity, oropharynx/hypopharynx), associations between patient survival and p53 status were ambiguous. METHODS: The authors examined a...

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Source

Identifiers

PMID: 21692053
DOI: 10.1002/cncr.25864

Genes

MDM2
MTBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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