Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of TP53 mutation-associated microRNAs predicts clinical outcome in head and neck squamous cell carcinoma patients.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Dec 2013

Ganci F, Sacconi A, Bossel Ben-Moshe N, Manciocco V, Sperduti I, Strigari L, Covello R, Benevolo M, Pescarmona E, Domany E, Muti P, Strano S, Spriano G, Fontemaggi G, Blandino G

Abstract excerpt

BACKGROUND: TP53 mutation is associated with decreased survival rate in head and neck squamous cell carcinoma (HNSCC) patients. We set out to identify microRNAs (miRNAs) whose expression associates with TP53 mutation and survival in HNSCC. PATIENTS AND METHODS: We analyzed TP53 status by direct sequencing of exons 2 through 11 of a prospective series of 121 HNSCC samples and assessed its association with outcome...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Squamous Cell
Share to Disease-Free Survival

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Head and Neck Neoplasms

Share to Kaplan-Meier Estimate

Share to MicroRNAs

Share to Multivariate Analysis

Share to Neoplasm Recurrence, Local

Share to Proportional Hazards Models

Source

Open in PubMed Open full text

Identifiers

PMID: 24107801
DOI: 10.1093/annonc/mdt380
PMCID: PMC3841017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of TP53 mutation-associated microRNAs predicts clinical outcome in head and neck squamous cell carcinoma patients.PMID 24107801Read ↗

A TP53 mutation model for the prediction of prognosis and therapeutic responses in head and neck squamous cell carcinoma.Semantic proximity Read ↗

TP53 Mutations in Head and Neck Squamous Cell Carcinoma and Their Impact on Disease Progression and Treatment Response.Semantic proximity Read ↗

Computational analysis of TP53 mutational landscape unveils key prognostic signatures and distinct pathobiological pathways in head and neck squamous cell cancer.Semantic proximity Read ↗

TP53 mutations in head and neck cancer.Semantic proximity Read ↗

High-risk TP53 mutations predict poor primary treatment response of patients with head and neck squamous cell carcinoma.Semantic proximity Read ↗

Significance of TP53 mutation in treatment and prognosis in head and neck squamous cell carcinoma.Semantic proximity Read ↗

Targeted sequencing reveals TP53 as a potential diagnostic biomarker in the post-treatment surveillance of head and neck cancer.Semantic proximity Read ↗

The prognostic value of TP53 mutations in hypopharyngeal squamous cell carcinoma.Semantic proximity Read ↗

TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selectionSemantic proximity Read ↗

Value of p53 sequencing in the prognostication of head and neck cancer: a systematic review and meta-analysisSemantic proximity Read ↗

Specific TP53 mutations predict aggressive phenotype in head and neck squamous cell carcinoma: a retrospective archival study.Semantic proximity Read ↗

TP53 mutations and survival in squamous-cell carcinoma of the head and neck.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.