Article
Significance of TP53 mutation in treatment and prognosis in head and neck squamous cell carcinoma.
Biomarkers in medicine - 1 Jan 2021
Jin Yu, Qin Xing
Abstract excerpt
Background:TP53 is ranked as the most common mutated gene in head and neck squamous cell carcinoma (HNSCC). Results: The status of TP53 mutation was investigated on International Cancer Genome Consortium and The Cancer Genome Atlas database and TP53-related differentially expressed genes were screened out from transcriptome data and mutation information. A TP53-related prognostic gene signature (TIMP4, ONECUT2,...
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