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Article

Dosing equation for tacrolimus using genetic variants and clinical factors.

British journal of clinical pharmacology - 1 Dec 2011

Passey Chaitali, Birnbaum Angela K, Brundage Richard C, Oetting William S, Israni Ajay K, Jacobson Pamala A

Abstract excerpt

AIM: To develop a dosing equation for tacrolimus, using genetic and clinical factors from a large cohort of kidney transplant recipients. Clinical factors and six genetic variants were screened for importance towards tacrolimus clearance (CL/F). METHODS: Clinical data, tacrolimus troughs and corresponding doses were collected from 681 kidney transplant recipients in a multicentre observational study in the USA...

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Identifiers

PMID: 21671989
DOI: 10.1111/j.1365-2125.2011.04039.x
PMCID: PMC3244642

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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