Article
Using genetic and clinical factors to predict tacrolimus dose in renal transplant recipients.
Pharmacogenomics - 1 Oct 2010
Wang Ping, Mao Yong, Razo Juan, Zhou Xiaobo, Wong Stephen T C, Patel Samir, Elliott Erin, Shea Erin, Wu Alan H B, Gaber A Osama
Abstract excerpt
AIMS: Tacrolimus has a narrow therapeutic window and shows significant interindividual difference in dose requirement. In this study we aim to first identify genetic factors that impact tacrolimus dose using a candidate gene association approach, and then generate a personalized algorithm combini...
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