Article
Pharmacogenetic considerations for optimizing tacrolimus dosing in liver and kidney transplant patients.
World journal of gastroenterology - 28 Dec 2013
Provenzani Alessio, Santeusanio Andrew, Mathis Erin, Notarbartolo Monica, Labbozzetta Manuela, Poma Paola, Provenzani Ambra, Polidori Carlo, Vizzini Giovanni, Polidori Piera, D'Alessandro Natale
Abstract excerpt
The introduction of tacrolimus in clinical practice has improved patient survival after organ transplant. However, despite the long use of tacrolimus in clinical practice, the best way to use this agent is still a matter of intense debate. The start of the genomic era has generated new research areas, such as pharmacogenetics, which studies the variability of drug response in relation to the genetic factors...
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