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Article

Genetic polymorphisms in AURKA and BRCA1 are associated with breast cancer susceptibility in a Chinese Han population.

The Journal of pathology - 1 Dec 2011

Ruan Yuan, Song Ai-Ping, Wang Hui, Xie Yun-Tao, Han Ji-Yuan, Sajdik Constantin, Tian Xin-Xia, Fang Wei-Gang

Abstract excerpt

Centrosome defects can result in aneuploidy and genomic instability, and have important implications for breast cancer development. The Aurora-A and BRCA1 proteins interact and both are strongly involved in centrosome regulation. Genetic variants in these two genes may have an effect on breast cancer development. Here, we report a comprehensive single nucleotide polymorphism (SNP) and haplotype-tagging...

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Source

Identifiers

PMID: 21598251
DOI: 10.1002/path.2902

Genes

BRCA1
AURKA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic polymorphisms in AURKA and BRCA1 are associated with breast cancer susceptibility in a Chinese Han population.PMID 21598251Read ↗

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