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Article

Association of genetic polymorphisms in AURKA, BRCA1, CCNE1 and CDK2 with the risk of endometrial carcinoma and clinicopathological parameters among Chinese Han women.

European journal of obstetrics, gynecology, and reproductive biology - 1 Jan 2015

Zheng Li-Yuan, Song Ai-Ping, Chen Lan, Liu Dong-Ge, Li Xiang-Hong, Guo Hong-Yan, Tian Xin-Xia, Fang Wei-Gang

Abstract excerpt

OBJECTIVE: Centrosome aberrations and cell-cycle deregulations have important implications for the development of endometrial carcinoma. AURKA, BRCA1, CCNE1 and CDK2 genes play pivotal roles in centrosome duplication and cell-cycle regulation. This study aimed to investigate whether genetic polymorphisms in these four genes may contribute to endometrial carcinoma susceptibility and progression in Chinese Han...

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Source

Identifiers

PMID: 25463638
DOI: 10.1016/j.ejogrb.2014.11.001

Genes

AURKA
BRCA1
CCNE1
CDK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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