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Article

Genetic variation in cell cycle regulatory gene AURKA and association with intrinsic breast cancer subtype.

Molecular carcinogenesis - 1 Dec 2015

Taylor Nicholas J, Bensen Jeannette T, Poole Charles, Troester Melissa A, Gammon Marilie D, Luo Jingchun, Millikan Robert C, Olshan Andrew F

Abstract excerpt

AURKA is a putative low-penetrance tumor susceptibility gene due to its prominent role in cell cycle regulation and centrosomal function. Germline variation in AURKA was evaluated for association with breast cancer and intrinsic breast cancer subtypes in the Carolina Breast Cancer Study (CBCS), a population-based case-control study of African Americans (AA) and Caucasians (Cau). Tag and candidate single...

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Source

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Identifiers

PMID: 25328151
DOI: 10.1002/mc.22238
PMCID: PMC4402110

Genes

AURKA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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