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Article

Single nucleotide polymorphisms rs911160 in AURKA and rs2289590 in AURKB mitotic checkpoint genes contribute to gastric cancer susceptibility.

Environmental and molecular mutagenesis - 1 Dec 2017

Mesic Aner, Markocic Ela, Rogar Marija, Juvan Robert, Hudler Petra, Komel Radovan

Abstract excerpt

BACKGROUND: Single nucleotide polymorphisms (SNPs) in mitotic checkpoint genes could confer increased susceptibility to gastric cancer (GC). We investigated the association of Aurora kinase A (AURKA), Aurora kinase B (AURKB), Aurora kinase C (AURKC), Polo-like kinase 1 (PLK1) and Budding uninhibited by benzimidazol 3, yeast (BUB3) gene polymorphisms with GC risk. MATERIALS AND METHODS: Genotyping of 6 SNPs in...

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Source

Identifiers

PMID: 28843004
DOI: 10.1002/em.22129

Genes

AURKA
AURKB
AURKC
BUB3
PLK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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Single nucleotide polymorphisms rs911160 in AURKA and rs2289590 in AURKB mitotic checkpoint genes contribute to gastric cancer susceptibility.PMID 28843004Read ↗

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